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            <gmx:Anchor xlink:href="http://lod.bco-dmo.org/id/dataset/995462.rdf" xlink:actuate="onRequest">CTD profile data from R/V Atlantis cruise AT50-08 in the ETNP oxygen minimum zone</gmx:Anchor>
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        <gco:CharacterString>CTD profile data from R/V Atlantis cruise AT50-08 in the ETNP oxygen minimum zone Dataset Description:  Methods and Sampling: &amp;lt;p&amp;gt;Seawater samples (10 × 100 L) were collected during R/V &amp;lt;em&amp;gt;Atlantis&amp;lt;/em&amp;gt; cruise AT50-08 (Feb–Mar 2023) at two stations in the Oxygen Minimum Zone of the Eastern Tropical North Pacific (10–600 m depth). Samples were collected by CTD rosette, pre-filtered through 0.22 µm filters to remove cells and debris, and concentrated ~500× by tangential flow filtration (100 kDa cutoff).&amp;lt;/p&amp;gt;

&amp;lt;p&amp;gt;The resulting concentrates contained both viruses and extracellular vesicles (EVs). EVs were enriched on board using a lectin-based binding column. Transmission electron microscopy (JEOL JEM 1400, Stony Brook University CryoEM facility) confirmed EV enrichment after column purification.&amp;lt;/p&amp;gt;

&amp;lt;p&amp;gt;Subsequent EV analyses were performed at the University of Pennsylvania School of Veterinary Medicine EV Core Facility. Methods included size-based separation (SEC-HPLC, gravity-driven iZon column, density-gradient ultracentrifugation), particle quantification (resistive pulse sensing, nCS1; nanoparticle tracking analysis, NTA), and immunophenotyping (nanoscale flow cytometry; ExoView™ chip array). See related datasets.&amp;lt;/p&amp;gt;</gco:CharacterString>
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        <gmx:Anchor xlink:href="http://lod.bco-dmo.org/id/award/885369.rdf" xlink:title="OCE-2202723" xlink:actuate="onRequest">Funding provided by NSF Division of Ocean Sciences (NSF OCE) Award Number: OCE-2202723 Award URL: https://www.nsf.gov/awardsearch/show-award?AWD_ID=2202723</gmx:Anchor>
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	Name: ISO_DateTime_UTC
	Units: unitless
	Description: &lt;p&gt;Start date time of the cast associated with the provided measurements in UTC time. This field has been converted from the original NMEA_UTC_Time field.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005323.rdf
	Name: NMEA_Latitude
	Units: decimal degrees
	Description: &lt;p&gt;Latitude reported by the ship&amp;#039;s GPS/navigation system to the Sea-Bird acquisition system via NMEA. This coordinate represents the latitude during the start of the associated cast.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005324.rdf
	Name: NMEA_Longitude
	Units: decimal degrees
	Description: &lt;p&gt;Longitude reported by the ship&amp;#039;s GPS/navigation system to the Sea-Bird acquisition system via NMEA. This coordinate represents the longitude during the start of the associated cast.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005325.rdf
	Name: timeS
	Units: seconds
	Description: &lt;p&gt;Elapsed time since the start of the CTD data record.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005326.rdf
	Name: latitude
	Units: decimal degrees
	Description: &lt;p&gt;Latitude of the CTD observation in decimal degrees, positive north.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005328.rdf
	Name: longitude
	Units: decimal degrees
	Description: &lt;p&gt;Longitude of the CTD observation in decimal degrees, positive east and negative west.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005330.rdf
	Name: prDM
	Units: decibar (dbar)
	Description: &lt;p&gt;Pressure measured by the Paroscientific Digiquartz pressure sensor.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005331.rdf
	Name: t090C
	Units: degrees Celsius (C)
	Description: &lt;p&gt;Primary seawater temperature measured by the Sea-Bird temperature sensor using the ITS-90 temperature scale.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005332.rdf
	Name: t190C
	Units: degrees Celsius (C)
	Description: &lt;p&gt;Secondary seawater temperature measured by the second Sea-Bird temperature sensor using the ITS-90 temperature scale.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005333.rdf
	Name: c0S_M
	Units: S/m
	Description: &lt;p&gt;Primary seawater conductivity measured by the Sea-Bird conductivity sensor.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005334.rdf
	Name: c1S_M
	Units: S/m
	Description: &lt;p&gt;Secondary seawater conductivity measured by the second Sea-Bird conductivity sensor.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005335.rdf
	Name: CStarTr0
	Units: unitless
	Description: &lt;p&gt;Beam transmission measured by the WET Labs C-Star transmissometer.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005336.rdf
	Name: upoly0
	Units: not provided
	Description: &lt;p&gt;Auxiliary measurement from the user-defined polynomial sensor identified in the Sea-Bird configuration as MicroTOP (trace oxygen profiler).&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005337.rdf
	Name: flECO_AFL
	Units: mg/m^3
	Description: &lt;p&gt;Fluorescence measured by the WET Labs ECO-AFL/FL fluorometer.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005338.rdf
	Name: sbeox0V
	Units: V
	Description: &lt;p&gt;Raw output voltage from the Sea-Bird SBE 43 dissolved oxygen sensor.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005339.rdf
	Name: upoly2
	Units: not provided
	Description: &lt;p&gt;Auxiliary measurement from a user-defined polynomial sensor identified in the Sea-Bird configuration as STOX in situ.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005340.rdf
	Name: upoly1
	Units: not provided
	Description: &lt;p&gt;Auxiliary measurement from a second user-defined polynomial sensor identified in the Sea-Bird configuration as STOX in situ.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005341.rdf
	Name: spar
	Units: not provided
	Description: &lt;p&gt;Surface irradiance measured by the Biospherical/Licor SPAR sensor (deck-mounted sensor; does not submerge with CTD).&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005342.rdf
	Name: altM
	Units: meters (m)
	Description: &lt;p&gt;Altimeter range measured by the CTD-mounted altimeter, representing distance to the seafloor or another reflecting target.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005343.rdf
	Name: nbf
	Units: count (number of bottles)
	Description: &lt;p&gt;Number of bottles fired associated with the CTD observation.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005344.rdf
	Name: depSM
	Units: meters (m)
	Description: &lt;p&gt;Seawater depth calculated from pressure using the latitude specified during Sea-Bird processing.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005346.rdf
	Name: density00
	Units: g/m^3
	Description: &lt;p&gt;Seawater density calculated using the primary temperature and conductivity measurements (T/C (ρ)).&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005347.rdf
	Name: density11
	Units: g/m^3
	Description: &lt;p&gt;Seawater density calculated from the secondary temperature and conductivity measurements (T/C (ρ)).&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005348.rdf
	Name: sal00
	Units: PSU
	Description: &lt;p&gt;Practical salinity calculated using the primary temperature and conductivity measurements.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005349.rdf
	Name: sal11
	Units: PSU
	Description: &lt;p&gt;Practical salinity calculated using the secondary temperature and conductivity measurements.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005350.rdf
	Name: svCM
	Units: m/s
	Description: &lt;p&gt;Sound velocity calculated using the Chen–Millero equation from the primary CTD measurements.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005351.rdf
	Name: svCM1
	Units: m/s
	Description: &lt;p&gt;Sound velocity calculated using the Chen–Millero equation from the secondary CTD measurements.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005352.rdf
	Name: sbeox0ML_L
	Units: mL/L
	Description: &lt;p&gt;Dissolved oxygen concentration calculated from the Sea-Bird SBE 43 oxygen sensor.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005353.rdf
	Name: sbeox0Mm_Kg
	Units: umol/kg
	Description: &lt;p&gt;Dissolved oxygen concentration calculated from the Sea-Bird SBE 43 oxygen sensor.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005354.rdf
	Name: dz_dtM
	Units: m/s
	Description: &lt;p&gt;CTD vertical descent rate calculated from changes in depth over time.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005355.rdf
	Name: T2_T190C
	Units: degrees Celsius
	Description: &lt;p&gt;Difference between the secondary and primary temperature measurements.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005356.rdf
	Name: flag
	Units: unitless
	Description: &lt;p&gt;Sea-Bird data flag associated with the observation.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005357.rdf
	Name: v1
	Units: V
	Description: &lt;p&gt;Raw voltage from auxiliary analog voltage channel 1. The physical measurement depends on the sensor connected to that channel for the particular CTD configuration.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005358.rdf
	Name: par
	Units: not provided
	Description: &lt;p&gt;Photosynthetically active radiation (PAR) measured by the underwater irradiance sensor mounted on the CTD package.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005359.rdf
	Name: sbeox0PS
	Units: unitless
	Description: &lt;p&gt;Dissolved oxygen measured by the primary Sea-Bird SBE 43 oxygen sensor, expressed as percent oxygen saturation.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005360.rdf
	Name: sbox0Mm_Kg_2
	Units: umol/kg
	Description: &lt;p&gt;Second processed dissolved oxygen concentration from the primary Sea-Bird SBE 43 oxygen sensor, expressed per unit mass of seawater.&lt;/p&gt; 
http://lod.bco-dmo.org/id/dataset-parameter/1005361.rdf
	Name: source_file_name
	Units: unitless
	Description: &lt;p&gt;Name of the original raw sensor file from which this data has been compiled.&lt;/p&gt; 
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This CSV file contains concatenated data from all of the originally provided Seabird CTD profile files, and is the primary data file for the dataset, CTD profiles from R/V Atlantis cruise AT50-08 in the ETNP Oxygen Minimum Zone. Thorough processing and  parameter details can be found on the metadata landing page for this BCO-DMO dataset.</gco:CharacterString>
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                <gco:CharacterString>&amp;lt;p&amp;gt;Seawater samples (10 × 100 L) were collected during R/V &amp;lt;em&amp;gt;Atlantis&amp;lt;/em&amp;gt; cruise AT50-08 (Feb–Mar 2023) at two stations in the Oxygen Minimum Zone of the Eastern Tropical North Pacific (10–600 m depth). Samples were collected by CTD rosette, pre-filtered through 0.22 µm filters to remove cells and debris, and concentrated ~500× by tangential flow filtration (100 kDa cutoff).&amp;lt;/p&amp;gt;

&amp;lt;p&amp;gt;The resulting concentrates contained both viruses and extracellular vesicles (EVs). EVs were enriched on board using a lectin-based binding column. Transmission electron microscopy (JEOL JEM 1400, Stony Brook University CryoEM facility) confirmed EV enrichment after column purification.&amp;lt;/p&amp;gt;

&amp;lt;p&amp;gt;Subsequent EV analyses were performed at the University of Pennsylvania School of Veterinary Medicine EV Core Facility. Methods included size-based separation (SEC-HPLC, gravity-driven iZon column, density-gradient ultracentrifugation), particle quantification (resistive pulse sensing, nCS1; nanoparticle tracking analysis, NTA), and immunophenotyping (nanoscale flow cytometry; ExoView™ chip array). See related datasets.&amp;lt;/p&amp;gt;</gco:CharacterString>
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                <gco:CharacterString>&amp;lt;p&amp;gt;CTD data were processed following standard Sea-Bird CTD procedures. Raw measurements were converted to engineering units using manufacturer calibration coefficients, then time-aligned across sensors (e.g., conductivity and oxygen aligned to pressure/temperature) and corrected for conductivity cell thermal mass.&amp;lt;/p&amp;gt;

&amp;lt;p&amp;gt;Data were screened to remove periods of unstable flow and package motion (surface soak, pump start-up, winch stops/pressure reversals/loops), and automated despiking (“wild edit”) was applied to remove dropouts and isolated spikes.&amp;lt;/p&amp;gt;

&amp;lt;p&amp;gt;Final profiles were generated from the downcast and used to compute derived variables including practical salinity, depth (from pressure using latitude), density, sound velocity (Chen–Millero), and dissolved oxygen products (µmol/kg, mL/L, % saturation); some oxygen fields include a smoothed/windowed version indicated in the headers (e.g., “WS=2”).&amp;lt;/p&amp;gt;</gco:CharacterString>
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          </gmd:processStep>
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                  <gco:CharacterString>- Loaded 10 CSV files (at5008055, at5008018, at5008037, at5008009, at5008004B, at5008029, at5008064, at5008048, at5008060, at5008049) using filenames as table names, with header row 1, empty rows removed, and empty string/&amp;quot;nd&amp;quot; values treated as missing
- Concatenated all 10 tables into a single table named &amp;quot;995462_v1_AT5008_ETNP_CTD_Profiles&amp;quot;, mapping matching columns across sources (including CStarTr0, NMEA Latitude, NMEA Longitude, NMEA UTC (Time), T2-T190C, altM, c0S/m, c1S/m, density00, density11, depSM, dz/dtM, flECO-AFL, flag, latitude, longitude, nbf, par, prDM, sal00, sal11, sbeox0ML/L, sbeox0PS, sbeox0V, sbox0Mm/Kg, sbox0Mm/Kg_2, spar, svCM, svCM1, t090C, t190C, timeS, upoly0, upoly1, upoly2, v1), and added a new &amp;quot;source_file_name&amp;quot; column recording the originating filename for each row
- Converted the &amp;quot;NMEA UTC (Time)&amp;quot; column (format &amp;quot;%b %d %Y  %H:%M:%S&amp;quot;, UTC) into a new &amp;quot;ISO_DateTime_UTC&amp;quot; datetime column formatted as &amp;quot;%Y-%m-%dT%H:%M:%SZ&amp;quot; in UTC
- Converted &amp;quot;NMEA Latitude&amp;quot; from degrees-decimal_minutes format (regex-parsed degrees/decimal_minutes/directional) into decimal degrees, overwriting the same column
- Converted &amp;quot;NMEA Longitude&amp;quot; from degrees-decimal_minutes format (regex-parsed degrees/decimal_minutes/directional) into decimal degrees, overwriting the same column
- Renamed columns: &amp;quot;NMEA UTC (Time)&amp;quot; to &amp;quot;NMEA_UTC_Time&amp;quot;, &amp;quot;NMEA Latitude&amp;quot; to &amp;quot;NMEA_Latitude&amp;quot;, &amp;quot;NMEA Longitude&amp;quot; to &amp;quot;NMEA_Longitude&amp;quot;, &amp;quot;c0S/m&amp;quot; to &amp;quot;c0S_M&amp;quot;, &amp;quot;c1S/m&amp;quot; to &amp;quot;c1S_M&amp;quot;, &amp;quot;flECO-AFL&amp;quot; to &amp;quot;flECO_AFL&amp;quot;, &amp;quot;sbeox0ML/L&amp;quot; to &amp;quot;sbeox0ML_L&amp;quot;, &amp;quot;sbox0Mm/Kg&amp;quot; to &amp;quot;sbeox0Mm_Kg&amp;quot;, &amp;quot;dz/dtM&amp;quot; to &amp;quot;dz_dtM&amp;quot;, &amp;quot;T2-T190C&amp;quot; to &amp;quot;T2_T190C&amp;quot;
- Reordered columns to: ISO_DateTime_UTC, NMEA_Latitude, NMEA_Longitude, NMEA_UTC_Time, timeS, latitude, longitude, prDM, t090C, t190C, c0S_M, c1S_M, CStarTr0, upoly0, flECO_AFL, sbeox0V, upoly2, upoly1, spar, altM, nbf, depSM, density00, density11, sal00, sal11, svCM, svCM1, sbeox0ML_L, sbeox0Mm_Kg, dz_dtM, T2_T190C, flag, v1, par, sbeox0PS, sbox0Mm_Kg_2, source_file_name
- Set column data types: numbers for most sensor/measurement columns (CStarTr0, NMEA_Latitude, NMEA_Longitude, T2_T190C, altM, c0S_M, c1S_M, density00, density11, dz_dtM, flECO_AFL, flag, latitude, longitude, par, prDM, sal00, sal11, sbeox0ML_L, sbeox0Mm_Kg, sbeox0PS, sbeox0V, sbox0Mm_Kg_2, spar, svCM, svCM1, t090C, t190C, timeS, v1), integers for depSM, nbf, upoly0, upoly1, upoly2, string for NMEA_UTC_Time and source_file_name, and datetime with format &amp;quot;%Y-%m-%dT%H:%M:%SZ&amp;quot; for ISO_DateTime_UTC
- Updated column metadata (descriptions, standard names, supplied units, and primary parameter flags) for all columns including CStarTr0, ISO_DateTime_UTC (marked primary), NMEA_Latitude, NMEA_Longitude, NMEA_UTC_Time, T2_T190C, altM, c0S_M, c1S_M, density00, density11, depSM (marked primary), dz_dtM, flECO_AFL, flag, latitude (marked primary), longitude (marked primary), nbf, par, prDM, sal00, sal11, sbeox0ML_L, sbeox0Mm_Kg, sbeox0PS, sbeox0V, sbox0Mm_Kg_2, source_file_name, spar, svCM, svCM1, t090C, t190C, timeS, upoly0, upoly1, upoly2, v1
- Deleted the &amp;quot;NMEA_UTC_Time&amp;quot; column
- Rounded &amp;quot;NMEA_Latitude&amp;quot;, &amp;quot;NMEA_Longitude&amp;quot;, &amp;quot;latitude&amp;quot;, and &amp;quot;longitude&amp;quot; columns to 6 decimal places, preserving trailing zeros
- Output the final table as 995462_v1_AT5008_ETNP_CTD_Profiles.csv</gco:CharacterString>
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                    <gmd:sourceCitation>
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