Instrument: Multiangle Light Scattering Detector

A multiangle light scattering (MALS) detector is a form of static light scattering detector which allows the absolute molecular weight (Mw) and potentially the radius of gyration (Rg) of a sample to be measured. Multiangle light scattering (MALS) describes a technique for determining structure by measuring the change in direction or energy of scattered visible light at a number of different angles, none of which are close to the angle of incidence of the light. It is used for determining both the absolute molar mass and the average size of molecules in solution, by detecting how they scatter light.